In this presentation, music therapists will hear case examples of the use of live heartbeat sounds through a Bluetooth stethoscope entrained with live music to address self-regulation, self-esteem, and resilience. Offering an overview of emerging neuroscience research on the brain-body equilibrium, the session will cover how music supports interoception and self-awareness in ways that can also modulate mood, emotions, and self-regulation. These concepts are relevant to music therapists worldwide as they provide a framework by which to understand the holistic and neurobiological impact of rhythm and music on the human body, securing the perspective that music therapy is neurologically, biologically, and psychologically beneficial as a standalone therapy when implemented through an intentional, evidence-based framework. Suggestions for incorporating live biofeedback into sessions, using a neurobiological approach to interdisciplinary collaboration, and implications for multiple populations will be discussed.